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If your pet gets into this substance, lower amounts may just increase tiredness About Press Copyright Contact us Creators Advertise Developers Terms Privacy Policy & Safety How YouTube works Test new features Press Copyright Contact us Creators. Trazodone works by helping to restore the balance of a certain natural chemical (serotonin) in the brain. Before these changes in 2018, the NHS spent around £569 million a year on prescriptions for medicines that can be bought from a pharmacy or supermarket, such as paracetamol You might want to increase back to 50mg for a few days, say possibly another 4 to 5, then drop it back down to 25 mg. Is trazodone a safe medication. You can get the vitamins and minerals you need from eating a healthy, varied and balanced diet, or buy them at a pharmacy or supermarket. 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